Apolipoprotein B100
Alternative Names
ApoB100; Apoprotein B100
Definition
Apolipoprotein B100 (apo B100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein (LDL).
This article discusses the test used to measure the level of apoB100 in the blood.
How the Test is Performed
How to Prepare for the Test
Your health care provider may tell you not to eat or drink anything for 4 - 6 hours before the test.
How the Test Will Feel
When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the Test is Performed
Most often, this test is done to help determine the cause or specific type of hyperlipidemia.
Normal Results
The normal range is 50 - 150 mg/dL.
Normal value ranges may vary slightly among different laboratories. Some laboratories use different measurements or may test different specimens. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
An abnormal result may mean you have high lipid levels (hyperlipidemia).
Other disorders that may be associated with high apoB100 levels include angina pectoris and heart attack.
Risks
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
- Multiple punctures to locate veins
Considerations
Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.
References
Genest J, Libby P. Lipoprotein disorders and cardiovascular disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA:Saunders Elsevier; 2011:chap 47.
Semenkovich, CF. Disorders of lipid metabolism. In: GoldmanL, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 213.